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You are invited to take part in a research study!

Taking part in a research study is a fantastic way to help future patients and gain access to potential new treatments. Read on to find out if you could take part in this research study.

What is the research study about?

Ezintsha Research Centre is conducting a study to see if CagriSema, a new medicine, can be used to treat people with cardiovascular (heart) disease.

This study will see if CagriSema can reduce the risk of having cardiovascular events (like heart attack and stroke).

Who is eligible to take part in the study?

The study is looking for very specific people. If you:

  • Are 55 years or older
  • Have previously had a heart attack (myocardial infarction) or brain attack (stroke) or have been diagnosed with poor circulation (peripheral arterial disease).
  • Are living with overweight or obesity ( BMI ≥ 25 kg/m2)
  • May also have Type 2 diabetes and / or chronic kidney disease.

Who cannot take part?

  • Women cannot take part if they are pregnant, breastfeeding or plan to get pregnant during the study period. Women who are able to become pregnant must use highly effective birth control throughout the study and will be counselled on the use of birth control.
  • You cannot take part in this study if you are already taking part in another study that is testing a medicine or treatment.
  • You must also not join other studies that are testing a medicine or treatment if you decide to take part in this study. This is to protect your safety and the outcome of the study.

The study will last for up to 4.5 years.
You will have up to 27 clinic visits with the study doctor or study staff.

Where in the country will the study take place?

In Johannesburg.

Participants will have to attend visits at the clinic in Parktown every month at first. After 6 months it is more flexible with 3 monthly visits.

What will participants get?

Expert medical care and education from a dedicated team of doctors and nurses. Regular health check-ups as part of the study.

Will participants be paid?

Yes, participants will receive a transport reimbursement of R405 at every visit.

Who to contact if you are interested?

For more information visit

If you have any questions, concerns or complaints about this study, please contact:

  • Dr N. Chandiwana
    076 164 3215 / 011 084 4950
  • Dr E. Bhaskar
    082 618 7851
have you ever had a heart attack or stroke - research study

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Sweet Life is a registered NPO/PBO (220-984) with a single goal: to improve diabetes in South Africa. We are funded by sponsorships and donations from aligned companies and organisations who believe in our work. We only share information that we believe benefits our community. While some of this information is linked to specific brands, it is not an official endorsement of that brand. We believe in empowering people with diabetes to make the best decisions they can, to live a healthy, happy life with diabetes.